Heterocycles Award

Does Nature Prefer Heterocycles?

Does Nature Prefer Heterocycles?

Award 2007 Winners Academic Award

Innovation and Benefits A fundamental aspect of chemistry involves creating chemical bonds between carbon atoms. Chemical processes commonly used to make such bonds usually also generate significant amounts of waste. Professor Krische developed a broad new class of chemical reactions that make bonds between carbon atoms using hydrogen and metal catalysts. This new class of reactions can be used...

Adventures with heterocycles.

Elucidation of mechanisms and discovery of novel reactions are interconnected, as four research chapters from the Munich laboratory demonstrate. 1) In a new opening of the furan ring, 2-methoxyfuran and tetra-acceptor-substituted ethylenes furnish methyl acrylates, which are cis-3-substituted by a cyclopropyl ring that bears the four acceptor groups. Experiments with trans- and cis-1,2-bis(trif...

Indoles and Related Heterocycles

Indole and the related heterocycles have emerged as efficient building blocks for the creation of novel anion receptors. This chapter focuses on the employment of indoles, carbazoles, and indolocarbazoles in the creation of molecular clefts, macrocycles, oligomers, and sensors. The majority of these structures utilize the heterocyclic NH as a hydrogen bond donor in binding to anions of various ...